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NF-kB p65 Mouse Monoclonal Antibody (14H2)
NF-kB p65 Mouse Monoclonal Antibody (14H2)
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
Catalog No:
FY-IG0386
Regular price
$239.00 USD
Regular price
Sale price
$239.00 USD
Unit price
/
per
1.5 weeks
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Product Details
Application(s)
WB, IHC, IP
Species Reactivity
Human, Mouse, Rat
Source
Murine
Ab Type
Monoclonal
Isotype
IgG1
Immunogen
Synthetic Peptide
Dilution
WB 1:1,000-3,000 IHC 1:200 IP 1:200
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. Store at -20°C. Avoid repeated freeze-thaw cycles. Stable for one year from the date of shipment.
Regulatory Status
For Research Use Only
