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Biotinylated Human TGF-beta 1 (N-Avi)
Biotinylated Human TGF-beta 1 (N-Avi)
Biotinylated Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed with a Avi tag at the N-terminus.
Catalog No:
EPT203
Regular price
$1,339.00 USD
Regular price
Sale price
$1,339.00 USD
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per
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Product Details
Accession
P01137
Molecular Weight
14.6 KDa
Apparent Molecular Weight
12-18 KDa, reducing conditions
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.001ng/µg (0.01EU/µg) as determined by LAL test.
Expression Host
Mammalian
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping Condition
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed in the Storage field.
Storage Condition and Shelf Life
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Analyte
TGF-beta 1
Regulatory Status
For Research Use Only
