• Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Acetyl NF kB P65(K314/K315) (EM1377) Mouse mAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Acetyl NF kB P65(K314/K315) (EM1377) Mouse mAb diluted at 1:200.
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Acetyl NF kB P65 (K314/K315) (5G11) Mouse mAb

Acetyl NF kB P65 (K314/K315) (5G11) Mouse mAb

NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.

Catalog No: EM1377
$148.00 USD
$148.00 USD
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Packaging
1.5 weeks
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Product Details

Application(s) IHC
Species Reactivity Human, Mouse, Rat
Source Murine
Isotype IgG1
Immunogen Synthetic Peptide
Concentration 1 mg/mL
Dilution IHC 1:100-200
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Analyte NF-kB p65
Regulatory Status For Research Use Only
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